AgingResearch.NewsJoin free

HER-2/NEU

There are 2 papers on HER-2/NEU in aging research: none in people yet, 2 in animals.

Gene

2 papers study it2 findings

HGNCNCBI GeneTaxon

See all 2 papers on HER-2/NEU

At a glance

The findings reach mice, none yet in people. 2 independent labs in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Includes the processes named after it and trials of drugs aimed at it.

  • 2 independent labs in 1 country
  • Animals2

Effects

2

extrinsic apoptosis

downin mice1

1 study

  1. HER-2/NEU decreases extrinsic apoptosis in mice (HER-2/Neu transgenic mice).

    “HER-2/Neu expression leads to the extrinsic apoptotic pathway suppression”

    AnimalsHER-2/Neu transgenic micehypothalamus

    FAS- and TNF-dependent ways participation in apoptosis mechanisms in hypotalumus in physiological and pathological aging

    Advances in gerontology = Uspekhi gerontologii

Cell death

downin mice1

1 study

  1. HER-2/NEU decreases cell death in mice (pathological aging; effect depended on stage of ontogenesis and animal genotype).

    “Enhanced expression of HER-2/neu determines low rate of cell death in the studied brain regions during pathological ageing.”

    Animalspathological aging; effect depended on stage of ontogenesis and animal genotypecortex, hippocampus, hypothalamus

    Analysis of HER-2/neu Receptor Expression and the Level of Neuronal Apoptosis in HER-2/neu Transgenic Mice during Aging

    Bulletin of experimental biology and medicine

Latest

Related