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CASPASE-8

There are 2 papers on CASPASE-8 in aging research: none in people yet, 2 in animals.

Gene

2 papers study it2 findings

See all 2 papers on CASPASE-8

At a glance

The findings reach mice, none yet in people. 2 independent labs in 2 countries.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Includes the processes named after it and trials of drugs aimed at it.

  • 2 independent labs in 2 countries
  • Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior and 4 more
  • Animals2

Effects

1

Cell survival

upin rats1

1 study

  1. CASPASE-8 increases cell survival in areas of atrophic epithelium.

    “an increase in cell survival induced by caspase-8”

    Animalsin areas of atrophic epitheliumprostate epithelium

    Profile of cell proliferation and apoptosis activated by the intrinsic and extrinsic pathways in the prostate of aging rats

    The Prostate

Associations

1

Apoptosis

upin mice1

1 study

  1. CASPASE-8 is associated with apoptosis in hypothalamus during aging, wild-type FVB/N mice.

    “caspase-8 expression is activated in hypothalamus in FVB/N mice (wild type) during aging, and it correlates with an increase in the apoptosis level”

    Animalsin hypothalamus during aging, wild-type FVB/N micehypothalamus

    FAS- and TNF-dependent ways participation in apoptosis mechanisms in hypotalumus in physiological and pathological aging

    Advances in gerontology = Uspekhi gerontologii

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