GPR39
- 1 lab
- Funders: Instituto de Salud Carlos III and 1 more
- Animals1
Interventions
1Alternate-day fasting + liraglutide
upin rats1
1 study
Alternate-day fasting + liraglutide
upin rats1
Alternate-day fasting + liraglutide increases GPR39 in rats.
“Proteomic analysis revealed significant upregulation of G protein-coupled receptor 39 (GPR39) and transmembrane protein 41b (Tmem41b) in the A+L group”
Animalsin high-fat diet-fed ratsliver5 weeks
The Proteomic Analysis of Intermittent Fasting Alone or with GLP-1RA in NAFLD Rats
ADA Scientific Sessions 2025 abstract
Funding
4 grants since 2016National Institute on AgingUS$4.2mInstituto de Salud Carlos III€385.4k
GPR39 as a Therapeutic Target in Aging-Related Vascular Cognitive Impairment and Dementia
National Institute on AgingOregon Health & Science UniversityUS$2.2m2023–2026
Role of GPR39 in Aging-Related Vascular Cognitive Impairment (VCI)
National Institute on AgingOregon Health & Science UniversityUS$2m2022–2025
Instituto de Salud Carlos IIIInstituto de Investigación Sanitaria de Santiago€183.9k2019–2021
Instituto de Salud Carlos IIIFundación Ramón Domínguez€201.5k2016–2018