Translational Lung Cancer Research
Gene variant linked to lower lung cancer risk in former smokers
Former smokers carrying a longevity-linked gene variant had lower relative lung cancer risk than noncarriers, with a hazard ratio of 0.42.Former smokers carrying a longevity-linked gene variant had lower relative lung cancer risk than noncarriers, with a hazard ratio of 0.42.
Cohort · 4,339 peopleLung cancer
Who was studied4,339 ever-smoking American men of Japanese ancestry, 28 years
What changedFormer smokers carrying FOXO3-G had lower lung cancer risk than FOXO3-TT carriers (hazard ratio 0.42)
The catchOnly 180 lung cancer cases supported analyses split by smoking status and genotype