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FDXR

Gene

3 papers2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Foundation for the National Institutes of Health and 2 more
  • Animals3

Effects

2

Liver steatosis

downin mice1

1 study

  1. FDXR protects against liver steatosis in mice.

    “and liver steatosis”

    Animalsshown by Fdxr+/- and Trp53+/- mice

    Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1-SREBP pathway

    Oncogene4 Feb 2022

More on Liver steatosis

Tumor

downin mice1

1 study

  1. FDXR protects against tumor in mice.

    “were prone to spontaneous tumors”

    Animalsshown by Fdxr+/- and Trp53+/- mice

    Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1-SREBP pathway

    Oncogene4 Feb 2022

More on Tumor

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