FBXL21
None of its findings points the other way.
- 1 lab in 1 country
- Animals2
- In silico1
Effects
1Lifespan
no changein silico1
1 study
Lifespan
no changein silico1
FBXL21 has no effect on lifespan in silico.
“In contrast, no such connection is observed for Fbxl21 in the Laurasiatheria superorder.”
In silicoin Laurasiatheria
Biology
Associations
3Lifespan
upin dogs1upin silico1
2 studies
Lifespan
upin dogs1upin silico1
FBXL21 is associated with lifespan in silico.
“least conserved Fbxl21 gene in the Euarchontoglires superorder exhibits a statistically significant connection of genomic characteristics”
In silicoin Euarchontoglires
Biology
FBXL21 is associated with lifespan in dogs.
“genes TDRP, MC2R, FBXO25 and FBXL21 are associated with longevity in Cane corso dogs”
Animals
Four novel genes associated with longevity found in Cane corso purebred dogs
BMC veterinary research
Body weight
upin silico1
1 study
Body weight
upin silico1
FBXL21 is associated with body weight in silico.
“significant connection of genomic characteristics (the median of dN/dS for a gene relative to all the other orthologous genes of a taxon, as well as the preference or avoidance of certain amino acids in its protein) with species-specific lifespan and body weight.”
In silicoin Euarchontoglires
Biology
Longevity
upin dogs1
1 study
Longevity
upin dogs1
FBXL21 is associated with longevity in dogs.
“SNPs with particular nucleotides were significantly overrepresented in long-lived dogs in four genes, TDRP, MC2R, FBXO25 and FBXL21.”
AnimalsCane Corso dogs; exon SNP encoding a tryptophan-for-arginine substitution
Four novel genes associated with longevity found in Cane Corso purebred dogs
Research SquarePreprint