FAM49B
- 1 lab in 1 country
- Funders: National Institute of Neurological Disorders and Stroke and 1 more
- Humans1
Effects
1Inflammation
downin human cells1
1 study
Inflammation
downin human cells1
FAM49B inhibits inflammation in human cells.
“Downregulation of microglial FAM49B, as observed in the SNpc of aging individuals, led to significant alterations in these cellular functions, which are associated with increased microglial activation.”
Cellsdownregulation
npj aging19 Dec 2025
Upstream
1Age
downin human cells1
1 study
Age
downin human cells1
Age decreases FAM49B in human cells.
“FAM49B is critically expressed in microglia of the human SNpc and is downregulated with age and PD.”
Cellssubstantia nigra pars compacta
npj aging19 Dec 2025