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EWS::FLI1

Gene

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Children's Cancer Research Fund and 1 more
  • Cells1

Effects

1

LMNB1

upin human cells1

1 study

  1. EWS::FLI1 increases LMNB1 in human cells.

    “We find that EWS::FLI1 upregulates LMNB1 via repetitive GGAA motif recognition and acetylation codes in ES cells and EWS::FLI1-permissive mesenchymal stem cells”

    Cellsin ES cells and EWS::FLI1-permissive mesenchymal stem cells

    Pharmacological targeting of P300/CBP reveals EWS::FLI1-mediated senescence evasion in Ewing sarcoma

    Molecular cancer

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