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DOCK8

Gene

2 papers study it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Institute of Allergy and Infectious Diseases
  • Humans1
  • Cells1

Effects

1

Cell death

downin mouse cells1

1 study

  1. DOCK8 decreases cell death in mouse cells.

    “Dock8, allowing for cell shape integrity and survival during migration through complex environments.”

    Cellsduring migration through complex environments

    A Dock8-dependent mechanosensitive central actin pool maintains T cell shape and protects the nucleus during migration

    Science immunology

Funding

1 grant since 2018

National Institute of Allergy and Infectious DiseasesUS$394.7k

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