AgingResearch.NewsJoin free

DOCK11ANDDOCK10

There is 1 paper on DOCK11ANDDOCK10 in aging research: none in people yet, 1 in animals.

Gene

1 paper studies it1 finding

See all 1

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Center for Geriatrics and Gerontology
  • Animals1

Effects

1

Anti-bacterial IgM production

upin mice1

1 study

  1. DOCK11ANDDOCK10 increases anti-bacterial IgM production in mice (shown by Dock11/Dock10 double knockout).

    “The down-regulation of Ziz2/3 in B-1a cells appeared to be responsible for this defective IgM production, as demonstrated by Ziz2/3 double-knockout mice.”

    Animalsshown by Dock11/Dock10 double knockoutB-1a cell

    Involvement of Zizimin2/3 in the age-related defect of peritoneal B-1a cells as a source of anti-bacterial IgM

    International immunology

Latest

Related