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DEFA-RS1

Gene

1 paper studies it1 finding

See all 1

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of Diabetes and Digestive and Kidney Diseases and 5 more
  • Animals1

Interventions

1

Ethanol

downin mice1

1 study

  1. Ethanol decreases DEFA-RS1 in mice.

    “Ethanol-induced downregulation of expression of the gut-protective antimicrobial peptides Defa-rs1, Reg3b, and Reg3g was observed in aged, but not young mice.”

    Animals3 days

    Changes in gut microbiome correlate with intestinal barrier dysfunction and inflammation following a 3-day ethanol exposure in aged mice

    Alcohol (Fayetteville, N.Y.)

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