BTAF1

Gene

1 paper2 findings

  • 1 lab in 1 country
  • Funder: National Institutes of Health
  • Animals1

Effects

2

Megakaryocyte progenitor production

upin mice1

1 study
  1. BTAF1 increases megakaryocyte progenitor production in mice.

    “elevated expression of nBtaf1 drives the aging-associated overexpression of HSC and megakaryocyte progenitor (MkP) signature genes”

    Animalshematopoietic stem cells

    Chromatin reorganization drives overexpression of a Btaf1 variant underpinning hematopoietic aging

    Nature communications18 Mar 2026

HSC expansion

upin mice1

1 study
  1. BTAF1 increases HSC expansion in mice.

    “which contributes to HSC expansion and elevated MkP production in aged mice.”

    Animalshematopoietic stem cells

    Chromatin reorganization drives overexpression of a Btaf1 variant underpinning hematopoietic aging

    Nature communications18 Mar 2026

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