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BCAR1

Gene

2 papers study it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Wilhelm Sander-Stiftung
  • Humans1
  • Cells1

Interventions

1

Dasatinib + dexamethasone

downin human cells1

1 study

  1. Dasatinib + dexamethasone decreases BCAR1 in human cells.

    “Dasatinib and Dexamethasone combination treatment showed strong synergistic effects on Src and p130Cas phosphorylation and led to reduced p130Cas expression.”

    Cellscombination treatment in TSCC lines

    The Src family kinase inhibitor drug Dasatinib and glucocorticoids display synergistic activity against tongue squamous cell carcinoma and reduce MET kinase activity

    Cell communication and signaling : CCS

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