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adr-1

Gene

2 papers2 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Includes the processes named after it and trials of drugs aimed at it.

  • 2 independent labs in 1 country
  • Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 4 more
  • Model organisms2

Effects

2

daf-16

upin worms1

1 study

  1. adr-1 activates daf-16 in worms.

    “we found nrde-1, wago-1 , and adr-1 as positive regulators of DAF-16.”

    Model organisms

    The Nuclear RNAi Pathway Regulates DAF-16/FOXO to Control C. elegans Longevity and Dauer Entry

    bioRxiv (Cold Spring Harbor Laboratory)Oct 21, 2022Preprint

More on daf-16

circ-crh-1 biogenesis

mediatesin worms1

1 study

  1. adr-1 mediates circ-crh-1 biogenesis in worms.

    “Here, we found that the biogenesis of circ-crh-1 was regulated by the double-stranded RNA-binding protein ADR-1.”

    Model organisms

    Loss of circRNAs from the crh-1 gene extends the mean lifespan in Caenorhabditis elegans

    Aging cellJan 31, 2022

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