AgingResearch.NewsJoin free

AC006064.4-201

Gene

1 paper studies it3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Effects

3

CDKN1B

downin human cells1

1 study

  1. AC006064.4-201 decreases CDKN1B in human cells.

    “thereby destabilizing CDKN1B mRNA and decreasing the translation of CDKN1B”

    Cellsin chondrocytes

    LncRNA AC006064.4-201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1

    Biomarker research

More on CDKN1B

Osteoarthritis

downin mice1

1 study

  1. AC006064.4-201 protects against osteoarthritis in mice.

    “protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1”

    Animalsin vivocartilage

    LncRNA AC006064.4-201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1

    Biomarker research

More on Osteoarthritis

Cellular senescence

downin human cells1

1 study

  1. AC006064.4-201 decreases cellular senescence in human cells.

    “could alleviate senescence and regulate metabolism in chondrocytes”

    Cellsin chondrocytescartilage

    LncRNA AC006064.4-201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1

    Biomarker research

More on Cellular senescence

Latest

Related