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Saturday, 3 October 2026
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Cellular senescence
Senescent cells, the SASP, and the drugs that clear or quiet them.
Aging clocks
Epigenetic, blood-based and other measures of biological age.
mTOR & rapamycin
Nutrient sensing through mTOR, and the rapalogs that dial it down.
Partial reprogramming
Yamanaka factors, epigenetic reprogramming and cellular rejuvenation.
NAD+ & sirtuins
NAD+ precursors, sirtuins and the metabolism of aging cells.
Mitochondria
Mitochondrial function, mitophagy and energy decline with age.
Dietary restriction
Caloric restriction, fasting and time-restricted eating.
GLP-1 drugs
Semaglutide, tirzepatide and what incretin drugs do to aging.
Inflammaging
Chronic low-grade inflammation and the aging immune system.
Brain aging
Cognitive aging, neurodegeneration and the aging brain.
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