Type 2 diabetes risk

There are 3 papers on type 2 diabetes risk in aging research: 3 observational studies in people. The newest story, Oct 31, 2026: “EAT-Lancet diet linked to lower type 2 diabetes risk”.

Disease

3 papers study it141 more mention it3 findings

17 new papers in 30 daysSee all 145 papers on type 2 diabetes risk

“No statistically significant association between time-dependently modelled SELENOP and T2D risk was observed”
Selenoprotein P and type 2 diabetes risk in a large cohort of older German adultsRedox biology2026doi:10.1016/j.redox.2026.104463
  • Humans3
  • In silico1

Upstream

2

25-hydroxyvitamin D

no changein humans1OR 1.06

1 study
  1. 25-hydroxyvitamin D was not clearly linked with type 2 diabetes risk in humans (South Asians; genetically predicted serum concentration; BMI-unadjusted primary outcome) (OR = 1.06, 95% CI: 0.83-1.36; p = 0.630).

    “The primary IVW analysis showed no statistically significant association between genetically predicted 25(OH)D and T2D risk”

    HumansSouth Asians; genetically predicted serum concentration; BMI-unadjusted primary outcomen = 50,533

    Association Between Genetically Predicted 25-Hydroxyvitamin D and Type 2 Diabetes Risk in South Asians: An Exploratory Two-Sample Mendelian Randomization Study

    Endocrinology, diabetes & metabolism

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Endometriosis

no changein humans1HR 0.97

1 study
  1. Endometriosis was not clearly linked with type 2 diabetes risk in humans (Surgically confirmed endometriosis; no history of diabetes at inclusion) (HR 0.97, 95% CI 0.80–1.16).

    “Surgically-confirmed endometriosis was not associated with the risk of type 2 diabetes in this large cohort”

    HumansSurgically confirmed endometriosis; no history of diabetes at inclusionfemalesn = 83,582

    Association between endometriosis and risk of type 2 diabetes: Results from the prospective E3N cohort

    Maturitas

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Associations

2

Selenoprotein P

no changein humans1HR 1.08

1 study
  1. Selenoprotein P is associated with type 2 diabetes risk in humans (Time-dependently modeled concentrations; highest versus lowest quintile) (HR 1.08, 95% CI 0.89–1.30, Q5 versus Q1).

    “No statistically significant association between time-dependently modelled SELENOP and T2D risk was observed”

    HumansTime-dependently modeled concentrations; highest versus lowest quintileserumMedian follow-up 11.5 yearsn = 6,529

    Blood protein showed no clear diabetes link in older adults

    Redox biology

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Hessian-optimized XGBoost and Kolmogorov-Arnold Networks

upin silico1+93% accuracy

1 study
  1. Hessian-optimized XGBoost and Kolmogorov-Arnold Networks predict type 2 diabetes risk in silico across ten global cohorts (93.3% accuracy).

    “our system achieved 93.3% accuracy across ten global cohorts.”

    In silicoacross ten global cohorts

    Hessian-optimized ensembles and regional phenotyping: A precision pharmacology framework for type 2 diabetes risk stratification

    Indian Journal of Pharmacy and Pharmacology

Latest

Dec 2025: 0Jan 2026: 11Feb 2026: 10Mar 2026: 14Apr 2026: 1May 2026: 2Jun 2026: 6Jul 2026: 11Aug 2026: 15Sep 2026: 13Oct 2026: 11Nov 2026: 195 papers in 12 months
Redox Biology

Blood protein showed no clear diabetes link in older adults

The highest versus lowest blood protein levels had a relative diabetes risk estimate of 1.08, with uncertainty spanning no difference.The highest versus lowest blood protein levels had a relative diabetes risk estimate of 1.08, with uncertainty spanning no difference.

Cohort study of 6,529 peopleType 2 diabetes
Diabetologia

Fatty liver genetic subtypes linked to opposite diabetes risks

An observational genetic analysis in UK Biobank participants linked fatty liver subtypes to higher or lower glucose and diabetes risk, with replication in a Chinese…An observational genetic analysis in UK Biobank participants linked fatty liver subtypes to higher or lower glucose and diabetes risk, with replication in a Chinese cohort.

Genetic association studyMechanisms
Frontiers in Nutrition

EAT-Lancet diet linked to lower type 2 diabetes risk

People in the highest versus lowest quarters of two diet scores had lower relative diabetes risk, with hazard ratios of 0.83 and 0.85.People in the highest versus lowest quarters of two diet scores had lower relative diabetes risk, with hazard ratios of 0.83 and 0.85.

Accepted, not yet published: cohort · 155,413 peopleType 2 diabetes

See all 145 papers on type 2 diabetes risk