Skeletal-related events

Disease

1 paper2 findings

  • Humans1

Upstream

1

ZONULIN-1

no changein humans1

1 study
  1. ZONULIN-1 has no effect on skeletal-related events in humans (aHR 0.98, 95% CI, 0.58-1.67).

    “Conversely, this association was absent in participants with preserved immune status (CD4+ ≥500 cells/mm3; aHR 0.98; 95% CI, 0.58-1.67).”

    Humanspreserved immune status (CD4+ ≥500 cells/mm3)

    Immune status modifies the association between plasma zonulin-1 and skeletal-related events in treated HIV: a case-cohort study

    The journals of gerontology. Series A, Biological sciences and medical sciences24 Jul 2026

More on ZONULIN-1

Associations

1

ZONULIN-1

upin humans1

1 study
  1. ZONULIN-1 raises the risk of skeletal-related events in humans (aHR 5.14, 95% CI, 2.25-11.77).

    “In participants with suboptimal immune recovery (CD4+ <500 cells/mm3), higher zonulin-1 levels were associated with incident SREs (aHR 5.14; 95% CI, 2.25-11.77; interaction q < .001).”

    Humanssuboptimal immune recovery (CD4+ <500 cells/mm3)

    Immune status modifies the association between plasma zonulin-1 and skeletal-related events in treated HIV: a case-cohort study

    The journals of gerontology. Series A, Biological sciences and medical sciences24 Jul 2026

More on ZONULIN-1

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