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Second primary malignancy

Disease

1 paper3 findings

  • Humans1

Associations

3

Radiotherapy

upin humans1

1 study

  1. Radiotherapy raises the risk of second primary malignancy in humans (Pinteraction < 0.001, 36%).

    “There were strong synergistic interactions between RT and the proxy of smoking (Pinteraction < 0.001), accounting for 36% of potentially smoking-related SPMs in cervical cancer survivors.”

    Humansin cervical cancer survivorsfemales

    Second primary malignancies in cervical cancer and endometrial cancer survivors: a population-based analysis

    AgingMay 4, 2022

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Human papillomavirus

upin humans1

1 study

  1. Human papillomavirus raises the risk of second primary malignancy in humans (SIR 3.7, 95% CI: 2.9-4.6).

    “Cervical cancer survivors had a higher risk for developing potentially HPV and smoking-related SPMs, especially in the RT group (SIRHPV = 3.7, 95% CI: 2.9-4.6; SIRsmoking = 3.2, 95% CI: 2.8-3.6).”

    Humansin cervical cancer survivorsfemales

    Second primary malignancies in cervical cancer and endometrial cancer survivors: a population-based analysis

    AgingMay 4, 2022

More on Human papillomavirus

Smoking

upin humans1

1 study

  1. Smoking raises the risk of second primary malignancy in humans (SIR 3.2, 95% CI: 2.8-3.6).

    “Cervical cancer survivors had a higher risk for developing potentially HPV and smoking-related SPMs, especially in the RT group (SIRHPV = 3.7, 95% CI: 2.9-4.6; SIRsmoking = 3.2, 95% CI: 2.8-3.6).”

    Humansin cervical cancer survivorsfemales

    Second primary malignancies in cervical cancer and endometrial cancer survivors: a population-based analysis

    AgingMay 4, 2022

More on Smoking

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