Progression from mild cognitive impairment to Alzheimer's disease

Disease1 paper1 finding

  • Humans1

Associations

1

XGBoost model

upin silico1

1 study
  1. XGBoost model predicts progression from mild cognitive impairment to Alzheimer's disease in silico (AUC-ROC 0.9059 [0.8983–0.9134]; PR-AUC 0.9214 [0.9156–0.9272]).

    “an AUC-ROC of 0.9059 [0.8983-0.9134] and PR-AUC of 0.9214 [0.9156-0.9272] for the MCI to AD task.”

    In silicoNon-imputed data; mild cognitive impairment at baseline

    Model forecasts Alzheimer's progression before diagnosis · medRxiv · 7 Oct 2026 · Preprint

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medRxivHumansPreprint

Model forecasts Alzheimer's progression before diagnosis

In 15,727 participants, a model detected decline before diagnosis in 22.41% of people progressing from mild cognitive impairment to Alzheimer's…In 15,727 participants, a model detected decline before diagnosis in 22.41% of people progressing from mild cognitive impairment to Alzheimer's disease.