Postmastectomy lymphedema

1. GLP-1 receptor agonists lower the risk of postmastectomy lymphedema in humans (HR 0.373, 95% CI 0.324–0.429).

   “GLP-1 receptor agonist exposure was associated with lower postmastectomy lymphedema risk in time-to-event analysis (hazard ratio 0.373, 95% CI 0.324–0.429; p < 0.001).”

   Humansafter mastectomy and/or axillary procedures650 daysn = 61,630

   Glucagon-like Peptide-1 Receptor Agonist Use and Risk of Postmastectomy Lymphedema in Breast Cancer Survivors: A Multicenter Real-World Cohort Study

   Research Square·2 Sep 2026Preprint

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