Melanoma-like tumors

1. vgll3 raises the risk of melanoma-like tumors in killifish.

   “Older mutant males develop melanoma-like tumors, validated via transplantation into immunodeficient rag2 models, and exhibit a shortened lifespan.”

   Animalsvgll3 mutantmales

   An antagonistically pleiotropic gene regulates vertebrate growth, maturity, and lifespan

   Nature communications·2 Jun 2026

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