Major adverse kidney events

Disease2 papers2 findings

  • Humans2

Associations

2

SGLT2 inhibitors

downin humans1

1 study
  1. SGLT2 inhibitors lower the risk of major adverse kidney events in humans (6.2 vs. 11.7%; hazard ratio 0.47).

    Humansin T2DM patients undergoing TEER1 year

    Outcomes of SGLT2 inhibitors after transcatheter mitral valve repair in patients with type 2 diabetes mellitus · Journal of cardiovascular medicine (Hagerstown, Md.) · 27 Aug 2026

SGLT2 inhibitors →

GLP-1 receptor agonists

downin humans1HR 0.63

1 study
  1. GLP-1 receptor agonists lower the risk of major adverse kidney events in humans (HR, 0.63; 95% CI, 0.48-0.81).

    Humansversus DPP-4i in men with prostate cancer undergoing ADT and T2Dmalesn = 659

    Glucagon-like peptide-1 receptor agonist versus other anti-diabetic agents on patients with prostate cancer undergoing androgen-deprivation therapy · Frontiers in urology · 7 Aug 2026

GLP-1 receptor agonists →

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Diabetes, Obesity & MetabolismHumans

GLP-1 drugs added to SGLT2 inhibitors linked to lower kidney risk

Adding a GLP-1 receptor agonist was linked to lower rates of major adverse kidney events (HR 0.70) compared with SGLT2 inhibitor monotherapy over 12…Adding a GLP-1 receptor agonist was linked to lower rates of major adverse kidney events (HR 0.70) compared with SGLT2 inhibitor monotherapy over 12 months.