Lung ischemia-reperfusion injury

1. Lung ischemia-reperfusion injury increases neutrophil infiltration in silico.

   “neutrophils showing marked infiltration in both injury and C1 groups.”

   In silicoin LIRI and C1 groupslung

   Exploration of genes associated with cellular senescence in lung ischemia-reperfusion injury and connection to immune infiltration

   Clinical and experimental medicine·11 Nov 2025

More on Neutrophil infiltration

1. Lung ischemia-reperfusion injury increases ABL2 in silico.

   “Subsequent WGCNA and machine learning approaches identified four signature genes (ABL2, CSF3, GCH1, NFKB2), which were consistently upregulated in both LIRI and C1 subtypes.”

   In silicoin LIRI and C1 subtypeslung

   Exploration of genes associated with cellular senescence in lung ischemia-reperfusion injury and connection to immune infiltration

   Clinical and experimental medicine·11 Nov 2025

More on ABL2

1. Lung ischemia-reperfusion injury increases CDKN1A in silico.

   “Differential analysis demonstrated upregulated expression of most pro-senescence genes, particularly CDKN1A in injured tissues.”

   In silicoin injured lung tissueslung

   Exploration of genes associated with cellular senescence in lung ischemia-reperfusion injury and connection to immune infiltration

   Clinical and experimental medicine·11 Nov 2025

More on CDKN1A

1. Lung ischemia-reperfusion injury increases senescence score in silico.

   “A total of 370 pro-senescence genes were screened for GSVA scoring revealing a significant elevation in senescence scores during LIRI.”

   In silicoin lung ischemia-reperfusion injurylung

   Exploration of genes associated with cellular senescence in lung ischemia-reperfusion injury and connection to immune infiltration

   Clinical and experimental medicine·11 Nov 2025

More on Senescence score