Isolated GH deficiency
1 paper3 findings
- Humans1
Effects
2Predicted brain age
no changein humans1
1 study
Predicted brain age
no changein humans1
Isolated GH deficiency has no effect on predicted brain age in humans.
“Predicted brain ages were similar between groups.”
HumansUntreated congenital isolated GH deficiency versus matched controlsbrain
Journal of endocrinological investigation16 Apr 2024
Absolute cortical thickness and regional brain volumes
no changein humans1
1 study
Absolute cortical thickness and regional brain volumes
no changein humans1
Isolated GH deficiency has no effect on absolute cortical thickness and regional brain volumes in humans.
“In IGHD, most absolute values of cortical thickness and regional brain volumes were similar to controls”
HumansUntreated congenital isolated GH deficiency versus matched controlsbrain
Journal of endocrinological investigation16 Apr 2024
Associations
1Normalized regional brain volumes
upin humans1
1 study
Normalized regional brain volumes
upin humans1
Isolated GH deficiency is associated with normalized regional brain volumes in humans.
“IGHD is primarily associated with similar absolute brain measurements, and a set of larger normalized volumes”
HumansUntreated congenital isolated GH deficiency versus matched controlsBilateral frontal pole and insula white matter; right insula and left caudate gray matter
Journal of endocrinological investigation16 Apr 2024