Influenza-like illness

There are 7 papers on influenza-like illness in aging research: 1 trial and 4 observational studies in people, 2 reviews.

Disease

7 papers study it7 more mention it3 findings

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“ILI diagnosed in the previous year was associated with increased risks of MACEs (aOR 1.24, 95% CI 1.18-1.29, P<.001)”
Association between influenza vaccination and reduced risks of major adverse cardiovascular events in elderly patientsAmerican heart journal2017doi:10.1016/j.ahj.2017.07.020
  • Human trial1
  • Humans4

Interventions

1

Dehydroepiandrosterone

no changein humans1

1 study
  1. Dehydroepiandrosterone showed no clear effect on influenza-like illness in humans.

    “Influenza-like morbidity during the winter was low in the study group with no difference between the DHEA and placebo groups.”

    Human trialp.o.50 mg qd4 consecutive daysn = 71

    Dehydroepiandrosterone treatment is not beneficial to the immune response to influenza in elderly subjects

    The Journal of clinical endocrinology and metabolism

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Associations

2

Mortality

upin humans1

1 study
  1. Influenza-like illness is associated with mortality in humans (over 7 of 12 significant seasons) (8.2% (95% CI, 7.5%-8.9%)).

    “ILI (8.2%; 95% CI, 7.5%-8.9%) (over the 7 of 12 significant seasons)”

    Humansover 7 of 12 significant seasons

    Mortality Associated with Infectious Diseases in Dutch Nursing Homes

    Journal of the American Medical Directors Association

Major adverse cardiovascular events

upin humans1

1 study
  1. Influenza-like illness is linked with a higher risk of major adverse cardiovascular events in humans (aOR 1.24, 95% CI 1.18-1.29).

    “ILI diagnosed in the previous year was associated with increased risks of MACEs (aOR 1.24, 95% CI 1.18-1.29, P<.001)”

    Humans

    Association between influenza vaccination and reduced risks of major adverse cardiovascular events in elderly patients

    American heart journal

More on Major adverse cardiovascular events

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