What does the research say about incident Parkinson's disease?

Incident Parkinson's disease

There is 1 paper on incident Parkinson's disease in aging research: 1 observational study in people. The newest story, Nov 7, 2026: “Some blood amino acids linked to lower Parkinson’s risk”.

Disease

1 paper studies it34 more mention it3 findings

2 new papers in 30 daysSee all 35 papers on incident Parkinson's disease

“Higher circulating levels of total BCAAs, leucine, and valine were associated with lower incident PD risk, with approximately linear inverse dose-response relationships.”

Circulating branched-chain amino acids and multimodal signatures of incident Parkinson’s disease: a prospective cohort studyNPJ Parkinson's disease2026doi:10.1038/s41531-026-01633-z

Humans1

Associations

Valine

downin humans1

1 study

Valine is associated with incident Parkinson's disease in humans (Free of Parkinson's disease and other neurodegenerative diseases at baseline).
“Higher circulating levels of total BCAAs, leucine, and valine were associated with lower incident PD risk, with approximately linear inverse dose-response relationships.”
HumansFree of Parkinson's disease and other neurodegenerative diseases at baselineplasman = 374,751
Some blood amino acids linked to lower Parkinson’s risk
NPJ Parkinson's diseaseNov 7, 2026

Latest

14 papers in 12 months

NPJ Parkinson's DiseaseNov 7

Some blood amino acids linked to lower Parkinson’s risk

A prospective cohort study of 374,751 UK Biobank participants linked higher levels of certain protein building blocks to a lower risk of developing Parkinson’s disease.A prospective cohort study of 374,751 UK Biobank participants linked higher levels of certain protein building blocks to a lower risk of developing Parkinson’s disease.

Cohort · 374,751 peopleParkinson's disease

Paper

Fundamental & Clinical PharmacologyOct 19

Two blood pressure drugs linked to lower Parkinson’s risk

Irbesartan and olmesartan had hazard ratios of 0.588 and 0.797 for Parkinson’s disease; the abstract did not specify the comparison drugs.Irbesartan and olmesartan had hazard ratios of 0.588 and 0.797 for Parkinson’s disease; the abstract did not specify the comparison drugs.

Cohort · 890,712 peopleParkinson's disease

Paper

Journal of Clinical MedicineAug 27

Vascular Risk Factors and the Risk of Incident Parkinson's Disease Among Stroke Survivors: A Nationwide Population-Based Cohort Study

Cohort study of 284,799 peopleParkinson's disease

Paper

Journal of Parkinson's DiseaseAug 20

Association of handgrip strength asymmetry with prodromal and incident Parkinson's disease: A prospective cohort study

Cohort study of 497,100 peopleParkinson's disease

Paper

International Health Sciences ReviewAug 19

Artificial intelligence in oculomics: A comprehensive review of ocular biomarkers for ophthalmic and systemic health

ReviewBiomarkers

Paper

Journal of Affective DisordersAug 8

Slowed movement in depression linked to Parkinson’s risk

For later Parkinson’s diagnosis, the hazard ratio—comparing rates over time—was 1.57 in people with depression and slowed movement and thinking versus those without…For later Parkinson’s diagnosis, the hazard ratio—comparing rates over time—was 1.57 in people with depression and slowed movement and thinking versus those without slowing.

Cohort · 6,326 peopleParkinson's disease