Incident incontinence: aging research evidence

Upstream

1

Depressive symptoms

mediatesin humans1HR 1.08

1 study

Depressive symptoms mediate incident incontinence in humans (14.88% mediated; natural indirect effect HR 1.08, 95% CI 1.03–1.12; P < 0.001).
“Depressive symptoms mediated 14.88% of the association in high-SLEs group, with statistically significant natural indirect effect”
HumansMediation of the association between high-SLEs exposure and incident incontinenceMedian follow-up of nine yearsfemalesn = 6,337
Stressful events linked to incontinence in women 45 and older
BMC public healthOct 20, 2026

Associations

1

Stressful life events

upin humans1HR 1.31

1 study

Stressful life events are associated with incident incontinence in humans (HR 1.31, 95% CI 1.00–1.71; P = 0.047).
“Compared to no-SLEs group, moderate-SLEs exposure was associated with a 31% increased risk of incontinence”
HumansModerate-SLEs exposure compared with no-SLEs; no baseline incontinence1–2 eventsMedian follow-up of nine yearsfemalesn = 6,337
Stressful events linked to incontinence in women 45 and older
BMC public healthOct 20, 2026

Latest

2 papers in 12 months

BMC Public HealthOct 21

Stressful events linked to incontinence in women 45 and older

At least three stressful life events were associated with an 88% higher relative risk of incontinence than no events over nine years’ median follow-up.At least three stressful life events were associated with an 88% higher relative risk of incontinence than no events over nine years’ median follow-up.

Cohort · 6,337 peopleUrinary incontinence

Paper

BMJ OpenFeb 10

Sleep disturbance and risk of incident incontinence in middle-aged and older Chinese adults: a 4-year national cohort study

Cohort study of 7,098 peoplePopulations