Impaired cognition

Disease

2 papers2 findings

Humans2

Associations

Subjective memory complaints

upin humans1OR 2.27

1 study

Subjective memory complaints raise the risk of impaired cognition in humans (OR 2.27, 95% CI 1.08-4.78, p=.03).
“older adults with subjective memory complaints had 2 times greater odds of having impaired cognition, after controlling for age, gender, and education (OR: 2.27, 95% CI: 1.08-4.78, p=.03)”
Humanscontrolling for age, gender, and educationn = 151
Subjective memory complaints and cognitive performance among older adults living in low-income senior housing communities: The moderating role of race
Geriatric nursing (New York, N.Y.)1 May 2025

Meal-task performance

downin humans1

1 study

Impaired cognition is associated with meal-task performance in humans.
“Among older adults, impaired cognition was associated with lower performance on both the sensical and nonsensical meals compared to normal cognition.”
HumansCompared with older adults with normal cognition
The effects of task novelty for age cohort and cognition level on memory for everyday virtual meal preparation tasks
Applied neuropsychology. Adult27 Jul 2024

Trial sponsors

First Affiliated Hospital of Chongqing Medical University
1 trialPhase 4132 people
Central South University
1 trialPhase 480 people
Vanderbilt University Medical Center
1 trialPhase 3438 people
Technical University of Munich
1 trialPhase 216 people

Latest

99 in 12 months

Journal of Clinical MedicineYesterday

Cognitive Impairment in Asthma: Emerging Evidence, Clinical Consequences, and Future Directions

ReviewMechanisms

Paper

bioRxiv15 Oct

A compound expands the brain stem-cell pool in aged mice

In an animal experiment, 18-month-old mice given the compound for 28 days also showed better spatial memory, without changes in movement.In an animal experiment, 18-month-old mice given the compound for 28 days also showed better spatial memory, without changes in movement.

Preprint: experiments in aged mice, 28 days, against untreated aged miceInterventions

Limit: Treatment lasted only 28 days, leaving the durability of stem-cell expansion unclear

Paper

Occupational Medicine12 Oct

A retrospective review of health profiles and functional capacity of elderly crane operators in Singapore

Cross-sectional study of 195 peoplePopulations

Paper

Geriatrics & Health Care10 Oct

A preliminary exploration of the association between hypertension and cognitive function and the mediating role of estimated glomerular filtration rate among older adults in a community in Shanghai

Cross-sectional study of 1,380 peopleHypertension

Paper

NPJ Aging7 Oct

Protein deficiency impaired memory in aging mice

Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell signalling and increased…Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell signalling and increased activity linked to inflammation.

Experiments in miceMechanisms

Paper

Bipolar Disorders1 Oct