High-burden multimorbidity

Disease

1 paper1 finding

  • Humans1

Associations

1

5-year mortality

upin humans1

1 study
  1. High-burden multimorbidity is associated with 5-year mortality in humans (Men: 17.8% versus 3.7%; women: 12.6% versus 2.4%).

    “to high-burden multimorbidity (5.9%; men 17.8% [95% CI 16.8-18.8], women 12.6% [95% CI 11.9-13.3]), with substantial gradients across intermediate profiles.”

    HumansHigh-burden multimorbidity compared with the disease-free profile5 yearsn = 510,372

    Rising illness burden linked to stalled US survival gains

    International journal of epidemiology18 Aug 2026

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International Journal of Epidemiology

Rising illness burden linked to stalled US survival gains

The disease-free share declined by nearly 1% annually, while most groups saw five-year death risks stall or rise after the mid-2000s.The disease-free share declined by nearly 1% annually, while most groups saw five-year death risks stall or rise after the mid-2000s.

Cohort study of 510,372 peoplePopulations