Hematopoietic defects

Papers on hematopoietic defects

11 papers

Friday, August 7

LeukemiaAug 7

SLF2 and SMC5 dysfunction drives HSC aging and predisposes to MDS, defining a new inherited bone marrow failure syndrome

Experiments in human cellsBones and joints

Saturday, February 21

bioRxivFeb 21

TRU-PE: A Universal, Trackable Prime Editor Toolkit for Robust Single- and Multi-Locus Genome Engineering

Preprint: experiments in human cellsInterventions

Thursday, June 26

EMBO ReportsJun 26

JMJD3-mediated senescence is required to overcome stress-induced hematopoietic defects

Experiments in miceCellular senescence

Friday, July 26

FEBS LettersJul 26

Age-associated myeloid malignancies - the role of STAT3 and STAT5 in myelodysplastic syndrome and acute myeloid leukemia

ReviewMechanisms

Saturday, September 16

bioRxivSep 16

Molecular and phenotypic blueprint of the hematopoietic compartment reveals proliferation stress as a driver of age-associated human stem cell dysfunctions

Preprint: study in peopleBlood and immune system

Saturday, August 28

AntioxidantsAug 28

Supplemental Ferulic Acid Inhibits Total Body Irradiation-Mediated Bone Marrow Damage, Bone Mass Loss, Stem Cell Senescence, and Hematopoietic Defect in Mice by Enhancing Antioxidant Defense Systems

Experiments in miceBones and joints

Thursday, July 29

Nature CommunicationsJul 29

Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis

Experiments in miceCellular senescence

Wednesday, June 16

The Journal of Experimental MedicineJun 16

Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS

ReviewImmune response

Wednesday, May 1

Journal of Pharmacological SciencesMay 1

The Sirt1 activator resveratrol improved hematopoiesis in pancytopenia mice induced by irradiation

Experiments in miceResveratrol

Saturday, March 19

OncotargetMar 19

BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

Experiments in miceCell cycle regulation

Monday, December 15

PNASDec 15

Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors

Experiments in miceTP53