Development or worsening of diabetic complications

1. 7-CpG DNAmAA predicts development or worsening of diabetic complications in humans (OR 1.11 per year of baseline DNAmAA; p=0.045).

   “increased the risk for developing of one or more additional complications or worsening of an already existing complication during the follow-up period by 11% in male participants”

   Humanstype 2 diabetes mellitus; adjusted for baseline DCSI, chronological age, smoking, alcohol, diabetes medication, and BMIper additional year of baseline DNAmAAMean 7.4 yearsmalesn = 56

   DNA Methylation Age Acceleration, Type 2 Diabetes, and its Complications: Cross-sectional and Longitudinal Data from the Berlin Aging Study II (BASE-II)

   medRxiv·Jun 28, 2022Preprint

More on 7-CpG DNAmAA