Colorectal cancer detection

There are 2 papers on colorectal cancer detection in aging research: none in people yet, 1 review. The newest story, Oct 6, 2026: “Colonoscopy linked to more cancer detection in older adults”.

Disease

2 papers study it9 more mention it2 findings

7 new papers in 30 daysSee all 11

  • In silico1

Interventions

1

Next-generation multitarget stool DNA testing

upin silico1

1 study
  1. Next-generation multitarget stool DNA testing increases colorectal cancer detection in silico (+11% CRC cases detected vs colonoscopy).

    “Over 10 years per 1,000 individuals offered screening, ng mt-sDNA detected 13% more precancerous lesions and 11% more CRC cases than colonoscopy”

    In silico10 years

    Model-based evaluation of colorectal cancer screening effectiveness: three rounds of multitarget stool DNA testing versus one colonoscopy

    Journal of medical economics

More on Next-generation multitarget stool DNA testing

Associations

1

Shield blood-based assay

upin humans1

1 study
  1. Shield blood-based assay predicts colorectal cancer detection in humans (average-risk screening population in the ECLIPSE study) (83.1% sensitivity for CRC; 13.2% sensitivity for advanced precancerous lesions).

    “the Shield blood-based assay demonstrated 83.1% sensitivity for CRC, whereas the sensitivity for advanced precancerous lesions was only 13.2%.”

    Reviewaverage-risk screening population in the ECLIPSE study

    Cell-Free DNA-Based Blood Tests for Colorectal Cancer Screening: Current Advances, Challenges, and Future Perspectives

    Diagnostics (Basel, Switzerland)

More on Shield blood-based assay

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 1Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 1Sep 2026: 1Oct 2026: 5Nov 2026: 010 papers in 12 months
JGH Open

Colonoscopy linked to more cancer detection in older adults

Five-year cancer detection was higher with colonoscopy than with no early colonoscopy: the hazard ratio, comparing event rates over time, was 1.78; overall mortality was…Five-year cancer detection was higher with colonoscopy than with no early colonoscopy: the hazard ratio, comparing event rates over time, was 1.78; overall mortality was unchanged.

Cohort study of 70,399 peopleColonoscopy

See all 11