There are 6 papers on advanced precancerous lesions in aging research: 3 observational studies in people, 3 reviews.
6 papers study it8 more mention it3 findings
3 new papers in 30 daysSee all 14
“This study evaluates a noninvasive stRNA test-FIT that markedly improves the detection of APLs and early colorectal cancers compared with FIT alone.”
- Humans3
Associations
3Mm-stRNA test
upin humans1
1 study
Mm-stRNA test
upin humans1
Mm-stRNA test predicts advanced precancerous lesions in humans (versus FIT alone) (97.1% vs 76.5%/70.6% CRC sensitivity, 83.8% vs 45.6%/36.8% APL sensitivity).
“This study evaluates a noninvasive stRNA test-FIT that markedly improves the detection of APLs and early colorectal cancers compared with FIT alone.”
Humansversus FIT alonen = 265
Cancer prevention research (Philadelphia, Pa.)
Circulating tumor DNA
upin humans1
1 study
Circulating tumor DNA
upin humans1
Circulating tumor DNA predicts advanced precancerous lesions in humans (advanced precancerous lesions screening) (sensitivity 0.13 (95% CI 0.12-0.14), specificity 0.90 (95% CI 0.88-0.91)).
“For APL, pooled sensitivity was 0.13 (95% CI 0.12-0.14) and specificity 0.90 (95% CI 0.88-0.91).”
Reviewadvanced precancerous lesions screening
Critical reviews in oncology/hematology
NDRG4 methylation
upin humans1
1 study
NDRG4 methylation
upin humans1
NDRG4 methylation is associated with advanced precancerous lesions in humans (advanced precancerous lesion vs normal control tissue) (higher in APL vs normal controls; P < 0.0001 in both 45-49 and 50-64 groups).
“NDRG4 levels were also statistically higher in APL case versus normal control samples in both the 45-49 (P < 0.0001) and 50-64 (P < 0.0001) year age groups.”
Humansadvanced precancerous lesion vs normal control tissuecolorectal tissue
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology