Boerhaave syndrome

There are 2 papers on Boerhaave syndrome in aging research: none in people yet.

Disease

2 papers study it1 more mentions it2 findings

1 new paper in 30 daysSee all 3 papers on Boerhaave syndrome

“persistent vomiting after self-escalation of a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist prescribed for weight loss, culminating in a contained oesophageal perforation.”
An Injection Leading to Oesophageal Perforation: A Rare Case of Contained Boerhaave's Syndrome Following Unsupervised GLP-1/GIP Receptor Agonist Dose EscalationCureus2026doi:10.7759/cureus.101811

Associations

2

Semaglutide

upin humans1

1 study
  1. Semaglutide is associated with Boerhaave syndrome in humans (semaglutide therapy for weight loss).

    “a 62-year-old female patient who developed Boerhaave syndrome two days after initiating semaglutide therapy for weight loss.”

    Humanssemaglutide therapy for weight lossesophagustwo days after initiationfemalesn = 1

    Boerhaave Syndrome: Case Report on a Rare Complication of Semaglutide Use

    Cureus

More on Semaglutide

gip/GLP-1 receptor agonists

upin humans1

1 study
  1. gip/GLP-1 receptor agonists raise the risk of Boerhaave syndrome in humans following severe vomiting induced by dose escalation.

    “persistent vomiting after self-escalation of a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist prescribed for weight loss, culminating in a contained oesophageal perforation.”

    Human trialfollowing severe vomiting induced by dose escalationfemalesn = 1

    An Injection Leading to Oesophageal Perforation: A Rare Case of Contained Boerhaave's Syndrome Following Unsupervised GLP-1/GIP Receptor Agonist Dose Escalation

    Cureus

More on gip/GLP-1 receptor agonists

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