There is 1 paper on whole blood serotonin in aging research: 1 trial in people.
1 paper studies it4 findings
“In ovariectomised women, the blood serotonin levels were inversely correlated with age (P < 0.01).”
- Human trial1
Interventions
1Estrogen
upin humans1
1 study
Estrogen
upin humans1
Estrogen increases whole blood serotonin in humans (postmenopausal women).
“Blood serotonin levels increased after oestrogen replacement in postmenopausal women to values similar to those observed in regularly menstruating women.”
Human trialpostmenopausal womenwhole bloodfemales
Blood serotonin levels in postmenopausal women: effects of age and serum oestradiol levels
Maturitas
Associations
3Reduced ovarian function
downin humans1
1 study
Reduced ovarian function
downin humans1
Reduced ovarian function is associated with whole blood serotonin in humans (compared with regularly menstruating women).
“Amenorrheic, natural postmenopausal and ovariectomised women had lower blood serotonin levels than regularly menstruating women.”
Humanscompared with regularly menstruating womenwhole bloodfemales
Blood serotonin levels in postmenopausal women: effects of age and serum oestradiol levels
Maturitas
Serum estradiol
upin humans1
1 study
Serum estradiol
upin humans1
Serum estradiol is associated with whole blood serotonin in humans (serum oestradiol levels ranging 30-1335 pg/ml).
“a direct relationship was observed between serum oestradiol levels and whole blood serotonin levels (P < 0.001).”
Humansserum oestradiol levels ranging 30-1335 pg/mlwhole bloodfemales
Blood serotonin levels in postmenopausal women: effects of age and serum oestradiol levels
Maturitas
Age
downin humans1
1 study
Age
downin humans1
Age is associated with whole blood serotonin in humans (ovariectomised women).
“In ovariectomised women, the blood serotonin levels were inversely correlated with age (P < 0.01).”
Humansovariectomised womenwhole bloodfemales
Blood serotonin levels in postmenopausal women: effects of age and serum oestradiol levels
Maturitas