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Volatile anesthetic concentration

Biomarker

1 paper1 finding

  • Human trial1

Interventions

1

Electroencephalography-guided anesthetic administration

downin humans1

1 study

  1. Electroencephalography-guided anesthetic administration decreases volatile anesthetic concentration in humans (0.69 vs 0.80 MAC; difference, -0.11 [95% CI, -0.13 to -0.10]).

    “Median end-tidal volatile anesthetic concentration was significantly lower in the guided group than the usual care group (0.69 vs 0.80 minimum alveolar concentration; difference, -0.11 [95% CI, -0.13 to -0.10)”

    Human trialundergoing major surgeryn = 1,213

    Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major Surgery: The ENGAGES Randomized Clinical Trial

    JAMA5 Feb 2019

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