Science Advances
Sustained mTORC1 activation in activated T cells impairs vaccine responses in older individuals
Experiments in miceBlood and immune system
Papers on vaccine responsiveness
289 papers9 new in 30 days
Friday, April 18
Friday, April 11
BMC Geriatrics
Impact of vitamin D levels on mortality in older covid-19 vaccinated patients
Cohort study of 126 peopleCOVID-19
Thursday, March 27
Sunday, March 23
Experimental Gerontology
Age-related peculiarities of antibody-mediated humoral immune response following SARS-CoV-2 infection
Cohort study in peopleImmune response
Thursday, March 20
Thursday, March 13
Sunday, March 9
Immunity & Ageing
CD31 + naïve T cells associate with immunosenescence and responsiveness to multiple vaccines in older adults
Cohort study in peopleBiomarkers
Friday, January 31
Trends in Molecular Medicine
A researcher's guide to studying sex differences in immune aging
ReviewImmune response
Sunday, January 26
EBioMedicine
Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traits
Cross-sectional study in peopleImmune response
Wednesday, January 1
GSA 2024 Abstract
INVESTIGATION OF TRANSCRIPTIONAL CHANGES IN IMMUNE CELL POPULATIONS OF MICE TREATED WITH RAPAMYCIN
Experiments in miceRapamycin
Wednesday, December 4
Science Translational Medicine
RANKL treatment restores thymic function and improves T cell-mediated immune responses in aged mice
Experiments in miceBlood and immune system
Tuesday, November 26
Wednesday, November 13
Advances in Immunology
Unravelling the contribution of lymph node fibroblasts to vaccine responses
ReviewImmune response
Tuesday, October 29
Journal of the American Geriatrics Society
Vaccinations in older adults: Optimization, strategies, and latest guidelines
ReviewVaccination
Friday, October 25
Mechanisms of Ageing and Development
Challenges of infectious diseases in older adults: From immunosenescence and inflammaging through antibiotic resistance to management strategies
ReviewInflammation
Friday, September 27
Science Advances
Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population
Cohort study of 234 peopleImmune response
The Lancet Infectious Diseases
Optimising vaccine immunogenicity in ageing populations: key strategies
ReviewInterventions
Monday, August 19
Sunday, August 4
Nature Communications
Multiple vaccine comparison in the same adults reveals vaccine-specific and age-related humoral response patterns: an open phase IV trial
Non-randomized trial in 315 peopleInterventions
Saturday, July 13
International Journal of Molecular Sciences
Pathology of Diabetes-Induced Immune Dysfunction
ReviewImmune response
Monday, June 24
Wednesday, May 29
medRxiv
Baseline immunotypes and immune entropy are indicators of multiple vaccine responsiveness
Preprint: cohort study in peopleBiomarkers
Sunday, May 5
bioRxiv
Haem toxicity in the aged spleen impairs T-cell immunity through iron deprivation
Preprint: experiments in miceBlood and immune system
Saturday, May 4
Vaccine
Changes in depressive symptoms and antibody production following influenza vaccination in adolescents and adults
Cohort study of 148 peopleDepression
Saturday, April 27
Tuesday, March 12
Tuesday, February 6
Tuesday, January 23
Tuesday, January 2
GeroScience
Tobacco exposure, but not aging, shifts the frequency of peripheral blood B cell subpopulations
Cross-sectional study in peopleBlood and immune system
Tuesday, December 26
Aging Cell
Pre-vaccination immunotypes reveal weak and robust antibody responders to influenza vaccination
Cohort study of 307 peopleMechanisms