Urolithin C glucuronide

Biomarker

1 paper1 finding

Human trial1

Associations

Cortical thickness

upin humans1

1 study

Urolithin C glucuronide is associated with cortical thickness in humans (β = 0.017 [95% CI, 0.002-0.031] per 1-SD).
“its glucuronide conjugate (β = 0.017 [95% CI, 0.002-0.031] per 1-SD) were associated longitudinally with preservation of cortical thickness”
HumansCognitively healthy participants allocated to the walnut diet; association with changes in urinary urolithin C glucuronide.cerebral cortex2 yearsn = 55
Gut metabolites linked to preserved brain thickness in older adults
Food & function7 Oct 2026

Latest

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Food & Function7 Oct

Gut metabolites linked to preserved brain thickness in older adults

In a 104-person trial sub-study, rising levels of gut-produced urolithins tracked with preserved cortical thickness over two years in 55 older adults eating walnuts.In a 104-person trial sub-study, rising levels of gut-produced urolithins tracked with preserved cortical thickness over two years in 55 older adults eating walnuts.

Cohort study of 104 peopleInterventions

Paper

Urolithin C glucuronide

Associations

Latest

Gut metabolites linked to preserved brain thickness in older adults

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