Unrepaired DNA damage

1 paper studies it21 more mention it

Humans1

Latest

2 papers in 12 months

Biology of ReproductionJun 11

Genome integrity checkpoints in mammalian oogenesis

ReviewCell cycle regulation

Genes & DevelopmentApr 15

A dual role for cGAS in shaping cellular and organismal responses to genomic instability

Experiments in killifishDNA damage response

Cell & BioscienceAug 3

DNA damage response and cell fate decisions across the lifespan: from fetal development to age-related respiratory diseases

ReviewDNA damage response

International Journal of Molecular SciencesApr 17

The Complex Interactions Between HIV-1 and Human Host Cell Genome: From Molecular Mechanisms to Clinical Practice

ReviewMechanisms

EBioMedicineJul 15

Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels

Cohort study in peopleDNA damage response

Molecular MetabolismJun 7

DNA damage to β cells in culture recapitulates features of senescent β cells that accumulate in type 1 diabetes

Experiments in mouse cellsDNA damage response

Journal of the Endocrine SocietyDec 16

GH and Senescence: A New Understanding of Adult GH Action

ReviewMechanisms

International Journal of Molecular SciencesNov 28

In Vivo Renin Activity Imaging in the Kidney of Progeroid Ercc1 Mutant Mice

Experiments in animalsBiomarkers

Oxidative Medicine and Cellular LongevitySep 11

Vascular Ageing Features Caused by Selective DNA Damage in Smooth Muscle Cell

Experiments in animalsMechanisms

bioRxivJun 7

DNA damage models phenotypes of β cell senescence in Type 1 Diabetes

Preprint: experiments in cellsMechanisms