Tumour-infiltrating interferon-gamma+ immune cells

1 paper1 finding

Animals1

Interventions

1

ANTI-PD-L2

upin mice1

1 study

ANTI-PD-L2 increases tumour-infiltrating interferon-gamma+ immune cells in mice.
“αPD-L2 increases tumour-infiltrating interferon-γ+ immune cell prevalence and interferon-γ production in aged but not young melanoma-bearing hosts in an unexpectedly IL-17-dependent manner.”
Animalsin melanoma-bearing hosts
Anti-PD-L2 immunotherapy is efficacious against melanoma in aged hosts through IL-17 and IFNγ signalling
Nature communications19 Nov 2025

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Nature Communications20 Nov

Anti-PD-L2 immunotherapy is efficacious against melanoma in aged hosts through IL-17 and IFNγ signalling

Experiments in miceMelanoma