Tissue mycobacterial load

Older age has no effect on tissue mycobacterial load in mice.

“of old (17-19 months; M) and aged (31M) C57BL/6 mice was similar to that of young (2-4M) mice.”

AnimalsLow aerosol dose Mtb infectionMtb H37Rvlung, spleen, and liver100-120 cfuUp to 6 weeks post infection

Host immunosenescence compromises Mycobacterium tuberculosis clearance

Aging·4 May 2026