TFMethyl Clock

TFMethyl Clock improves chronological age prediction accuracy in silico.

“we developed an alternative, TFMethyl Clock model, outperforming several existing approaches.”

In silicoCompared with several existing epigenetic age prediction approaches

An improved epigenetic age estimation with TFMethyl Clock reveals DNA methylation changes during aging in transcription factor binding sites

bioRxiv (Cold Spring Harbor Laboratory)·7 Oct 2025Preprint