Telomere-associated DNA damage

Papers on telomere-associated DNA damage

11 papers1 new in 30 days

Tuesday, October 6

Regenerative TherapyOct 6

Stem cell senescence as a regenerative bottleneck in age-related skeletal degeneration: Mechanistic crosstalk and translational strategies

Core molecular mechanisms of stem cell senescence in skeletal degeneration.

ReviewCellular senescence

Sunday, May 31

Laboratory Investigation; a Journal of Technical Methods and PathologyMay 31

Telomere Shortening and p16-Associated Senescence in Myofibromas

Cross-sectional study of 33 peopleTelomerase and telomere maintenance

Thursday, April 2

EMBO Molecular MedicineApr 2

Tomatidine is a senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice

Experiments in miceInterventions

Thursday, March 12

iScienceMar 12

Replicative senescence induction in single cells is not predicted by telomere length, dysfunction, or oxidation

Experiments in human cellsTelomerase and telomere maintenance

Thursday, July 17

Aging CellJul 17

Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells

Experiments in miceTelomerase and telomere maintenance

Wednesday, July 12

GeroScienceJul 12

Determining the feasibility of characterising cellular senescence in human skeletal muscle and exploring associations with muscle morphology and physical function at different ages: findings from the MASS_Lifecourse Study

Cross-sectional study in peopleCellular senescence

Friday, April 28

GenesApr 28

Damage-Free Shortening of Telomeres Is a Potential Strategy Supporting Blind Mole-Rat Longevity

Experiments in cellsTelomerase and telomere maintenance

Tuesday, May 1

Cell MetabolismMay 1

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD⁺ Decline

Experiments in miceMetabolic dysfunction

Wednesday, February 21

Environmental PollutionFeb 21

TERT regulates telomere-related senescence and apoptosis through DNA damage response in male germ cells exposed to BPDE in vitro and to B[a]P in vivo

Experiments in ratsTelomerase and telomere maintenance

Tuesday, September 26

Aging CellSep 26

Gene therapy with the TRF1 telomere gene rescues decreased TRF1 levels with aging and prolongs mouse health span

Experiments in miceInterventions

Tuesday, September 2

Current BiologySep 2

DNA damage foci at dysfunctional telomeres

Experiments in human cellsTelomerase and telomere maintenance