Sympathetic activity

Biomarker

1 paper

  • Human trial1

Funding

8 grants since 2023

National Institute on AgingUS$1.7mNational Heart, Lung, and Blood InstituteUS$1.7mNational Institute on Alcohol Abuse and AlcoholismUS$528.8k

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Nature Communications

Microglial ALKBH5 loss protects fat browning in aging male mice

Knocking out the RNA demethylase ALKBH5 in microglia enhanced sympathetic innervation and preserved subcutaneous brown adipocytes in aging male mice.Knocking out the RNA demethylase ALKBH5 in microglia enhanced sympathetic innervation and preserved subcutaneous brown adipocytes in aging male mice.

Experiments in miceMechanisms