Soluble transferrin receptor

Biomarker

3 papers2 findings

  • Human trial1
  • Humans2

Upstream

2

Hepcidin

no changein humans1

1 study
  1. Hepcidin has no effect on soluble transferrin receptor in humans (r=0.082; p=0.438).

    “expected negative correlation between hepcidin and sTfR, observed in controls (Young, r=-0.533, p=0.006; Elderly, r=-0.473, p=0.017), was absent in HIV (r=0.082; p=0.438).”

    Humansvirologically suppressed chronic HIV infection under ARTmalesn = 92

    Dysregulation of iron metabolism modulators in virologically suppressed HIV-infected patients

    Frontiers in immunologyNov 25, 2022

More on Hepcidin

HIV infection

downin humans1

1 study
  1. HIV infection decreases soluble transferrin receptor in humans.

    “Compared to both healthy (Young and Elderly) groups, HIV exhibited decreased iron, transferrin saturation, and sTfR, and increased ferritin, but similar hepcidin levels.”

    Humansvirologically suppressed chronic HIV infection under ART vs healthy controlsmalesn = 92

    Dysregulation of iron metabolism modulators in virologically suppressed HIV-infected patients

    Frontiers in immunologyNov 25, 2022

More on HIV infection

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