Serum creatinine to cystatin C ratio

1. Serum creatinine to cystatin C ratio is associated with incident cardiovascular disease in humans (Quartile 4 versus quartile 1: HR 0.60 (95% CI, 0.47–0.75)).

   “Cox models showed that lower SI was significantly associated with an increased risk of incipient CVD.”

   HumansMiddle-aged and older Chinese adults; quartile 4 versus quartile 1; multivariable-adjusted analysisMedian follow-up of 3.0 years46.4% mensn = 8,589

   Association Between the Serum Creatinine to Cystatin C Ratio and Cardiovascular Disease in Middle-Aged and Older Adults in China: A Nationwide Cohort Study

   Journal of the American Heart Association·25 Apr 2025

More on Incident cardiovascular disease

1. Serum creatinine to cystatin C ratio is associated with cardiovascular disease in humans.

   “In the cross-sectional analysis, multivariate logistic regression revealed a significant negative association between SI and CVD.”

   HumansCross-sectional analysis of middle-aged and older Chinese adults46.1% mensn = 11,115

   Association Between the Serum Creatinine to Cystatin C Ratio and Cardiovascular Disease in Middle-Aged and Older Adults in China: A Nationwide Cohort Study

   Journal of the American Heart Association·25 Apr 2025

More on Cardiovascular disease