Response time inconsistency

Biomarker

3 papers7 findings

  • Humans3

Effects

1

Attention switching performance

downin humans1

1 study
  1. Response time inconsistency impairs attention switching performance in humans.

    “Greater RTI was associated with significantly slower attention switching performance between-persons and within-persons over time.”

    Humansbetween-persons and within-personsn = 304

    Associations among response time inconsistency, attention switching, and cognitive status: A measurement burst approach

    Neuropsychology1 Mar 2026

Associations

5

Cognitive impairment no dementia

upin humans1

1 study
  1. Response time inconsistency is associated with cognitive impairment no dementia in humans (p<.006 and p<.0001).

    “Covariate-adjusted multinomial logistic regression models revealed RTI was associated with increased odds of CIND-single (p<.006) and CIND-multiple (p<.0001) statuses.”

    Humansn = 4,241

    Prevalence and Correlates of Cognitive Impairment No Dementia (CIND) Status: The Midlife in the United States Study.

    GSA 2025 abstract31 Dec 2025

  2. Cognitive impairment no dementia is associated with response time inconsistency in humans (Cohen's d=.20, p<.01).

    “Response time inconsistency (RTI), an index of central nervous system integrity and impairment/dementia risk, was greater among CIND-single (Cohen’s d=.20, p<.01) and CIND-multiple (Cohen’s d=.52, p<.001) participants”

    Humansn = 4,241

    Prevalence and Correlates of Cognitive Impairment No Dementia (CIND) Status: The Midlife in the United States Study.

    GSA 2025 abstract31 Dec 2025

More on Cognitive impairment no dementia

Cognitive impairment

upin humans1

1 study
  1. Response time inconsistency is associated with cognitive impairment in humans.

    “Importantly, RTI-attention switching associations were specific to individuals exhibiting cognitive impairment.”

    Humansin cognitive impairment (CIND-S and CIND-M)

    Associations among response time inconsistency, attention switching, and cognitive status: A measurement burst approach

    Neuropsychology1 Mar 2026

More on Cognitive impairment

Self-rated health

downin humans1

1 study
  1. Response time inconsistency is associated with self-rated health in humans (r=-.13 to -.18, ps<.0001).

    “as well as poorer self-rated mental (r=-.13) and physical (-.18, ps<.0001) health.”

    Humansn = 4,285

    Development and Validation of Response Time Inconsistency in the Midlife in the United States (MIDUS) Study

    GSA 2025 abstract31 Dec 2025

Cognitive function

downin humans1

1 study
  1. Response time inconsistency is associated with cognitive function in humans (rs=-.19 to -.41, ps<.0001).

    “RTI was associated with slower task switching performance, lower scores on the BTACT, episodic memory, and executive function cognitive composites (rs=-.19 to -.41, ps<.0001)”

    Humansn = 4,285

    Development and Validation of Response Time Inconsistency in the Midlife in the United States (MIDUS) Study

    GSA 2025 abstract31 Dec 2025

Age

upin humans1

1 study
  1. Age is associated with response time inconsistency in humans (r=.26, p<.0001).

    “RTI was greater with age (r=.26, p<.0001)”

    Humansn = 4,285

    Development and Validation of Response Time Inconsistency in the Midlife in the United States (MIDUS) Study

    GSA 2025 abstract31 Dec 2025

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