Radiology Artificial Intelligence
MRI brain-age gap linked to later clinical worsening
Age estimates differed from actual ages by an average of 3.76 years in internal testing and 4.82–5.15 years in external testing.Age estimates differed from actual ages by an average of 3.76 years in internal testing and 4.82–5.15 years in external testing.
Cohort · 954 peopleBrain age
Who was studied954 people with normal cognition or various dementias
What changedLater clinical worsening was more likely with a larger brain-age gap (hazard ratio 1.92)
The catchChronological age was the training target, not a direct measure of biological brain aging