Nature Medicine
Semaglutide lowered pressure in a heart failure group with obesity
Among patients with obesity and heart failure with preserved ejection fraction, exercise pressure fell 9.8 millimeters of mercury with semaglutide versus a 0.9 rise with…Among patients with obesity and heart failure with preserved ejection fraction, exercise pressure fell 9.8 millimeters of mercury with semaglutide versus a 0.9 rise with placebo.
Randomized trial · 81 peopleSemaglutide
Who was studied81 patients with HFpEF and obesity, 52 weeks, against placebo
What changedPressure during exercise fell more with semaglutide than placebo (difference, −10.6 mmHg)
The catchThe main outcome was heart pressure rather than hospitalizations or survival
